Using System Restore in previous versions of Windows has been something of a gamble. There's no way of telling which applications or drivers it might affect - you just have to try it and see.
Windows 7 is different. Right-click Computer, select Properties > System Protection > System Restore > Next, and choose the restore point you'd like to use. Click the new button to 'Scan for affected programs' and Windows will tell you which (if any) programs and drivers will be deleted or recovered by selecting this restore point.